In a 2010 TED Talk focused on developing new technologies to drastically reduce carbon dioxide emissions, Bill Gates briefly mentioned reducing the rate of population growth. A conspiratorial video circulating on Facebook misleadingly edits Gates’ talk to suggest his “wish” was to depopulate the planet through vaccines.
Efficacy is a measure of how well a vaccine performs in a clinical trial. It specifically refers to a relative reduction in infection or disease when comparing the vaccinated group to the placebo (or control) group.
For instance, both the Pfizer/BioNTech and Moderna vaccines were primarily evaluated for their ability to prevent symptomatic COVID-19, with the former having a 95% efficacy and the latter having a 94% efficacy in the clinical trial data submitted for the original authorization by the Food and Drug Administration.
Common side effects of the COVID-19 vaccines include injection site pain, fatigue, headache, muscle pain and fever.
Data from the Pfizer/BioNTech and Moderna trials also show the side effects included joint pain and chills. These reactions are more likely after the second dose of those vaccines, given several weeks after the first, and are more common and severe in younger people.
The full ingredient list for any authorized or approved COVID-19 vaccine can be found on the Centers for Disease Control and Prevention website and in a variety of documents on the Food and Drug Administration’s website, including in a fact sheet for vaccine recipients that’s available in numerous languages.
Both the Pfizer/BioNTech and Moderna vaccines contain messenger RNA,
No vaccine or medical product is 100% safe, but the safety of vaccines is ensured via rigorous testing in clinical trials prior to authorization or approval, followed by continued safety monitoring once the vaccine is rolled out to the public to detect potential rare side effects. In addition, the Food and Drug Administration inspects vaccine production facilities and reviews manufacturing protocols to make sure vaccine doses are of high-quality and free of contaminants.
More than half a billion doses of COVID-19 vaccines have now been administered in the U.S. and only a few, very rare, safety concerns have emerged. The vast majority of people experience only minor, temporary side effects such as pain at the injection site, fatigue, headache, or muscle pain — or no side effects at all. As the Centers for Disease Control and Prevention has said, these vaccines “have undergone and will continue to undergo the most intensive safety monitoring in U.S.
All of the authorized and approved vaccines are effective at preventing severe COVID-19.
Against earlier forms of the coronavirus, the vaccines were highly effective at preventing symptomatic illness. For example, clinical trials for the Pfizer/BioNTech and Moderna mRNA vaccines and the protein-based Novavax vaccine found each reduced the risk of getting sick by more than 90%.
Subsequent studies have demonstrated that the vaccines are effective under real-world conditions.
The authorized or approved vaccines were initially tested in animals and early phase clinical trials, in which scientists evaluated different doses, checked for the expected immune responses and monitored for potential safety issues. To find out whether the shots prevent disease and are safe, the vaccines that passed the first set of tests were then evaluated in phase 3 trials.
The Moderna and Novavax phase 3 trials each included about 30,000 volunteers,
President Joe Biden boasts that the U.S. is on pace to be the first country in the world to vaccinate 100 million people. That’s true, but per capita the U.S. is not tops in the world in vaccinations.
Since the Centers for Disease Control and Prevention began recommending that members of the public mask up last spring, additional research has backed the use of face masks to combat the coronavirus, but knowledge gaps still remain. Here, we summarize the evidence.